Since you have clown loaches, we'd be hesitant to recommend it at all, as they do not react well to meds, not even at half doses. If the clown loaches are not ill, we highly, highly recommend you set up a quarantine tank to move the sick fish to and treat them there. And yes, dose once a day, but the water change can be just 10-20%. You just want to keep the water quality up, meds are hard on it. Treat until the fish are well, an average of 3-4 days but possibly as much as a week.
Date published: 2018-08-19